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中药资源方向

陈伟

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个人简介:

       陈伟,博士,教授,博士/硕士研究生导师。中国计算机学会生物信息学专委会委员、中国人工智能学会生物信息学专委会委员、中国生物工程学会生物信息学专委会委员、中国生物信息学会(筹)理事,四川省生物信息学会常务理事,Molecular Therapy-Nucleic Acids期刊副主编。

研究方向:

致力于生物信息学和系统生物学研究,基于中医药大数据和药用植物资源,采用人工智能方法开展多组学数据分析算法开发、医学大数据挖掘、药物发现与设计、药用植物功能基因组/比较基因组学等方面的研究。

课题组网站:https://chenweilab.cn/

代表性成果:

已主持完成国家和省部级项目10余项,获科睿唯安全球高被引科学家,爱思唯尔中国高被引学者,生物信息领域全球前2%顶尖科学家等荣誉称号;在Nucleic Acids Research, Molecular Therapy等期刊发表SCI论文150余篇,近三年代表性论文如下:

[1] Qiang Tang, Fulei Nie, Qi Zhao, Wei Chen*. (2022) A merged molecular representation deep learning method for blood-brain barrier permeability prediction. Briefings in Bioinformatics, 23(5):1-10.

[2] Fanbo Meng, Qiang Tang, Tianzhe Chu, Xianhai Li, Yue Lin, Xiaoming Song*, Wei Chen*. (2022) TCMPG: an Integrative Database for Traditional Chinese Medicine Plant Genome. Horticulture Research, 9: uhac060.

[3] Xianhai Li, Qiang Tang, Fanbo Meng, PufengDu*, Wei Chen*. (2022) INPUT: An intelligent network pharmacology platform unique for traditional Chinese medicine. Computational and Structural Biotechnology Journal, 20:1345-1351.

[4] Juanjuan Kang, Qiang Tang, Jun He, Le Li, Nianling Yang, Shuiyan Yu, Mengyao Wang, Yuchen Zhang, Jiahao Lin, Tianyu Cui, Yongfei Hu, Puwen Tan, Jun Cheng, Hailong Zheng, Dong Wang*, Xi Su*, Wei Chen*, Yan Huang*. (2021) RNAInter v4.0: RNA interactome repository with redefined confidence scoring system and improved accessibility. Nucleic Acids Research, 50(D1): D326-D332.

[5] Fanbo Meng, Tianzhe Chu, Qiang Tang, Wei Chen*. (2021) A tetraploidization event shaped the Aquilaria sinensis genome and contributed to the ability of sesquiterpenes synthesis. BMC Genomics, 22(1):647.

[6] Qiang Tang, Fulei Nie, Juanjuan Kang, Wei Chen*. (2021) mRNALocater: enhance the prediction accuracy of eukaryotic mRNA subcellular localization by using model fusion strategy. Molecular Therapy, 29(8):2617-2623.

[7] Qiang Tang, Juanjuan Kang, Jiaqing Yuan, Hua Tang, Xinahai Li, Hao Lin*, Jian Huang*, Wei Chen*. (2020) DNA4mC-LIP: a linear integration method to identify N4-methylcytosine site in multiple species. Bioinformatics, 36(11):3327-3335.

[8] Jun Wang, Pufeng Du*, Xinyu Xue, Guangping Li, Yuanke Zhou, Wei Zhao, Hao Lin, Wei Chen*. (2020) VisFeature: a stand-alone program for visualizing and analyzing statistical features of biological sequences. Bioinformatics, 36(4):1277-1278.

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