刘芳
一、个人简介
刘芳,副教授,中药学博士后,硕士生导师,澳大利亚昆士兰大学访问学者,入选四川省中医药管理局学术与技术带头人后备人选,在药学院从事科研与教学工作,研究方向:中药新制剂和新剂型、中医药大健康产品开发、中药炮制作用原理研究,主持国家自然科学基金青年基金、中国博士后科学基金、省科技厅、四川省社科联等各级各类科研课题,获得教育部科学技术进步奖(推广类)二等奖2项,四川省学位与研究生教育管理研究优秀成果奖1项,授权专利成果转化1项,指导学生参加第十六届全国大学术药苑论坛获得创新成果三等奖、四川省国际“互联网+”大学生创新创业大赛获得银奖等。兼任中华中医药学会中药制剂专委会委员,四川省适宜技术研究会常务理事,参编《中药药剂学实验》双语等教材3部,论著4部。
? 联系邮箱:297933995@qq.com Tel:15828345121
二、代表性成果(可含承担项目、发表论文、论著、获奖等)
?? 1. 近3年以通讯作者或第一作者发表的代表性论文
[1]Luping Yang, Yunjie Hu, Hongdan Deng, Yan Li, Ruiyuan Zhang, Qian Zhang, Li Yang, Huiwen Pang, Fang Liu*, Chaomei Fu*. Water-soluble polysaccharides from Torreya grandis nuts: Structural characterization and anti-inflammatory activity[J]. International Journal of Biological Macromolecules, 2025:138935.(一区7.7分)
[2]Ruiyuan Zhang, Caijia Shen, Yicheng Lei, Yao Song, Lin Li, Huiwen Pang, Chen Chen, Yichen Hu, Chaomei Fu, Fang Liu. Cinnamon (Cinnamomum) as a Food-Medicine Homologue: A Review of Pharmacological Mechanisms and Potential Applications in Metabolic Diseases. Food Reviews International,2025.(二区5.46)
[3]Yicheng Leia, Ruiyuan Zhanga, Yan Lia, Huiwen Pangb, Qiang Fuc, Chen Chend, Fang Liu*.Pueraria Radix and its major constituents against metabolic diseases:Pharmacological mechanisms and potential applications,Phytotherapy Research,2025(二区 6.9分)
[4]Qian Zhang, Hongdan Deng, Ruifeng Luo, Hu Qi, Yicheng Lei, Luping Yang, Huiwen Pang, Chaomei Fu, Fang Liu*.Oral food-derived whey protein isolate-Tremella fuciformis polysaccharides pickering emulsions with adhesive ability to delivery magnolol for targeted treatment of ulcerative colitis[J].International Journal of Biological Macromolecules, 2024:135585.(一区7.7分)
[5]Yiwen Bao, Ruiyuan Zhang, Xinyi Jiang, Fang Liu*, Yao He*, Huiling Hu, Xinlian Hou, Li Hao.Detoxification mechanisms of ginseng to aconite: a review[J],Journal of Ethnopharmacology,2023(二区)
[6]Ruiyuan Zhang, Fang Liu*, Qian Zhang, Luping Yang, Xinlian Hou, Taoming Du, Jie Fan, Huiling Hu, Hongdan Deng, Li Hao, Li Guo*, Chaomei Fu. Intra-articular delivery system of methotrexate for rheumatoid arthritis therapy: An in-suit thermosensitive comprehensive gel of polysaccharide from Aconitum carmichaelii Debx [J]. International Journal of Biological Macromolecules,2023,244:124822.(一区7.7分)
[7]Ruiyuan Zhang , qian Zhang, Shun Zhu, Biyang Liu, Fang Liu*, Yao Xu*. Mulberry leaf (Morus alba L.): A review of its potential influences in mechanisms of action on metabolic diseases[J], Pharmacology Research,2022, 175:106029(一区10.334分)(高被引论文)
[8]Shun Zhu, Fang Liu*, Ruiyuan Zhang, Zongxiang Xiong, Qian Zhang, Li Hao, Shiyin Chen*. Neuroprotective Potency of Neolignans in Magnolia officinalis Cortex Against Brain Disorders[J]. Frontier in Pharmacology,2022,13:857449(二区)
[9]Shaoyang Liu, Ruiyuan Zhang, Xing Zhang, Shun Zhu, Siyu Liu, JueYang, Zhiping Li, Tianhui Gao*, Fang Liu*, Hu Huiling.The Invasive Species Reynoutria japonica Houtt. as a Promising Natural Agent for Cardiovascular and Digestive System Illness[J], Frontier in Pharmacology,2022, 13:863707.(二区)
[10]Chunlei Wei , Jing Qiu, Yuyi Wu, Ziqiang Chen, Ziwei Yu, Zecheng Huang, Ke Yang, Huiling Hu*, Fang Liu*. Promising traditional Chinese medicine for the treatment of cholestatic liver disease process (cholestasis, hepatitis, liver fibrosis, liver cirrhosis)[J],Journal of Ethnopharmacology,2022,297(二区)
[11]Xiao Wang, Shu Fu, Chen Zhang, Xin Nie, Wan Liao, Ming Zhao, Fang Liu*. Gastroprotective Effect of Ethanol Extracts from Bark of Magnolia officinalis on Ethanol-Induced Gastric Mucosal Damage in Rats[J].Biomed Research International, 2021, 2021:6688414
[12]Xiao Wang, Chen Zhang, Mingyue Zheng,Fei Gao, Jinming Zhang*, Fang Liu*.Metabolomics Analysis of L-Arginine Induced Gastrointestinal Motility Disorder in Rats Using UPLC-MS After Magnolol Treatment[J], Frontiers in pharmacology, 2019, 10: 183.(二区,5.58分)
[13]邓鸿丹,张倩,刘芳*,杨璐萍,吴学渊,张芮苑.Box-Behnken响应面优化厚朴酚-分离乳清蛋白自组装纳米粒制备工艺及体外评价[J/OL].中华中医药学刊,2025
?[14]张倩,刘芳*,张芮苑,邓鸿丹,杨璐萍,任虹.厚朴挥发油纳米乳凝胶的制备及其对溃疡性结肠炎小鼠的药效评价[J].中草药,2024,55(3):746-756.
[15]刘芳,张芮苑,沈才佳,付欣怡,宋姚,雷以珵,庞惠文,刘洋,陈晨*,李杰*.基于胃脑相关探讨厚朴三物汤防治急性胃溃疡大鼠的作用机制[J].中草药,2024,55(16):5525-5540.
[16]张倩,张芮苑,邓鸿丹,王李琳,杨璐萍,刘芳*,任虹.中药厚朴产地加工发汗前后所含挥发油抗氧化活性及治疗溃疡性结肠炎药效研究[J].中华中医药学刊,2024,55(3):746-756
[17]刘芳,张芮苑,刘畅*,王潇,郝莉,杨璐萍.发汗前后厚朴对IBS-C大鼠肠道菌群分布及5-HT、SP水平的影响[J].中国实验方剂学杂志,2023,29(14):141-149.
[18]刘畅,邓鸿丹,杨璐萍,张芮苑,刘芳*,任虹.基于多指标的CRITIC-AHP复合加权评分法优选厚朴-大黄药对水提工艺研究[J].中药材,2023,46(12):3068-3075.
[19]刘畅,王潇,刘芳*,张芮苑,傅超美*,付贤华,周奇.厚朴酚对便秘型肠易激综合征大鼠5-HT通路及肠道菌群的影响[J].中成药,2023,45(9):3067-3072.
[20]刘思雨,周玮玲,刘芳*,石金凤,崔星,刘绍瑒.厚朴三物汤促进腹部手术后胃肠道恢复的Meta分析[J].中药药理与临床,2022,38(6):155-159.
2. 代表性课题
国家自然科学基金委员会,青年基金,81603300,基于“组分-效用-靶点”研究厚朴“发汗”增味减燥作用机制,主持
国家自然科学基金委员会,面上项目,81473354,基于体内分布及机体答应部位差异性的川木香煨制和归经趋向,参加
中国博士后基金,面上项目,2020M673569XB,基于5-HT信号系统研究川产道地药材厚朴产地加工“发汗”增效作用机制,主持
四川省科技厅,省自然科学基金面上项目,2023NSFSC0661 ,基于“成分-药性-药效”关联的“紫油厚朴”产地加工发汗作用机理研究,主持
四川省科技厅,应用基础研究计划,20YYJC0655,基于“药-证-效”关键质量属性传递的川产道地中药厚朴质控体系的研究,主持
四川省科技厅,苗子工程项目,2014-096,基于“构效信息-体内表征”模式研究厚朴产地“发汗”的机制,主持
四川省社会科学联合会,健康中国战略下绿色食品植物应用指南,主持
四川省教育厅,重点项目,16ZA0107,基于“谱效模型”研究厚朴产地加工“发汗”作用机制,主持
成都市科技局课题,基于附子多糖为载体的抗类风湿性关节炎原为温敏水凝胶的研究,主持