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中药制剂与炮制方向

罗开沛

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罗开沛,博士,博士后,副教授,硕士生导师,中药资源与鉴定硕士研究生第一党支部书记。2014年于重庆医科大学获中药学学士学位,2017年于立即博备用网址_立即博赌场-游戏平台获药剂学硕士学位,2021年于中国药科大学获药剂学博士学位。入选中华中医药学会青年人才托举工程,立即博备用网址_立即博赌场-游戏平台杏林学者“1313”高层次人才。

主要从事中药新型给药系统的研究。主持国家自然科学基金青年基金、中国博士后科学基金面上项目、四川省自然科学基金面上项目等科研项目7项。在国内外期刊发表学术论文50余篇,包括Small、Chemical Engineering Journal、Acta Biomaterialia、ACS Applied Materials & Interfaces等国际著名杂志,其中高被引论文1篇,封面论文1篇。为Journal of Nanobiotechnology、ACS Applied Materials & Interfaces等期刊审稿人。协助指导多名研究生获得国家奖学金、省级/校级优秀毕业生等荣誉。指导本科生荣获“全国大学生药苑论坛”创新成果一等奖和优秀论文奖,立项大学生创新创业课题3项。获优秀学士论文指导教师。

     联系方式:luokaipei@cdutcm.edu.cn

代表性成果

(一)承担项目

1. 国家自然科学基金青年基金,82204633,2023.01-2025.12,主持

2. 中国博士后科学基金面上项目,2021M700550,2021.12-2024.08,主持

3. 四川省自然科学基金面上项目,2022NSFSC0634,2022.01-2023.12,主持

4. 四川省科教联合基金面上项目,2024NSFSC2112,2024.11-2026.10,主持

5. 中华中医药学会(2024-2026年度)青年人才托举工程,2024-QNRC2-B28,主持

(二)发表论文

1.Kaipei Luo*, Lu Yang, Chunmei Yan, Yuxin Zhao, Qiuxia Li, Xing Liu, Long Xie, Qiang Sun, Xiaofang Li*. A dual-targeting liposome enhances triple-negative breast cancer chemoimmunotherapy through inducing immunogenic cell death and inhibiting STAT3 activation. Small, 2023, 19: 2302834.(IF: 13.3,中科院一区,封面论文)

2.Qiuxia Li, Xing Liu, Chunmei Yan, Bolin Zhao, Yuxin Zhao, Lu Yang, Mingyi Shi, Hua Yu*, Xiaofang Li*, Kaipei Luo*. Polysaccharide-based stimulus-responsive nanomedicines for combination cancer immunotherapy. Small, 2023, 19: 2206211.(IF: 13.3,中科院一区)

3.Kaipei Luo, Yunfei Lian, Min Zhang, Hua Yu, Guangji Wang, Juan Li*. Charge convertible biomimetic micellar nanoparticles for enhanced melanoma-targeted therapy through tumor cells and tumor-associated macrophages dual chemotherapy with IDO immunotherapy. Chemical Engineering Journal, 2021, 412: 128659.(IF: 16.744,中科院一区)

4.Kaipei Luo, Yi Gao, Shaoping Yin, Yawen Yao, Hua Yu*, Guangji Wang, Juan Li*. Co-delivery of paclitaxel and STAT3 siRNA by multifunctional nanocomplexes for targeted treatment of metastatic breast cancer. Acta Biomaterialia, 2021, 134: 650-664.(IF: 10.633,中科院一区)

5.Chunmei Yan, Yuxin Zhao, Xiaolian Liu, Yingjie Jiang, Qiuxia Li, Lu Yang*, Xiaofang Li*, Kaipei Luo*. Self-delivery Nano-booster to Enhance Immunogenic Cell Death for Cancer Chemoimmunotherapy. ACS Applied Materials & Interfaces, 2024, 16: 33169-33181.(IF: 9.5,中科院二区)

6.Chunmei Yan, Qiuxia Li, Qiang Sun, Lu Yang, Xing Liu, Yuxin Zhao, Mingyi Shi, Xiaofang Li*, Kaipei Luo*. Promising nanomedicines of shikonin for cancer therapy. International Journal of Nanomedicine, 2023, 18: 1195-1218.(IF: 8.0,中科院二区,ESI高被引论文)

7.Kaipei Luo, Shaoping Yin, Ruixia Zhang, Hua Yu, Guangji Wang, Juan Li. Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy. International Journal of Pharmaceutics, 2020, 589: 119870.(IF: 6.51,中科院二区)

8.Kaipei Luo, Feng Xu, Tianyi Yao, Jianping Zhu, Hua Yu, Guangji Wang, Juan Li*. TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem enhances the targeted therapy of chemotherapeutic agent against multidrug-resistant cancer. International Journal of Biological Macromolecules, 2021, 183: 1270-1282.(IF: 8.025,中科院一区)

9.Yingjie Jiang, Chunmei Yan, Minghao Li, Siying Chen, Zhimin Chen*, Lu Yang*, Kaipei Luo*. Delivery of natural products via polysaccharide-based nanocarriers for cancer therapy: A review on recent advances and future challenges. International Journal of Biological Macromolecules, 2024, 278: 135072.(IF: 7.7,中科院一区,本科生一作)

10.Lu Yang, Xianfeng Liu, Siyin Chen, Jiayi Sun, Yiwen Tao, liyuan Ma, Yong Zeng, Kaipei Luo*, Ruimin Tian*, Xianli Meng*. Scutellarin Ameliorates Mitochondrial Dysfunction and Apoptosis in OGD/R-Insulted HT22 Cells through Mitophagy Induction. Biomedicine & Pharmacotherapy, 2024, 179: 117340.(IF: 6.9,中科院二区)

 

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