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中药制剂与炮制方向

罗开沛

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一、个人简介

罗开沛,特聘副研究员,硕士生导师(破格),中药资源与鉴定硕士研究生第一党支部书记中国药科大学药剂学博士,立即博备用网址_立即博赌场-游戏平台中药学博士后。入选中华中医药学会青年人才托举工程,立即博备用网址_立即博赌场-游戏平台杏林学者1313”高层次人才。

主要从事中药纳米递释系统的研究。主持国家自然科学基金青年基金、中国博士后科学基金面上项目、四川省自然科学基金面上项目等科研项目7。在国内外期刊发表学术论文50余篇,包括SmallChemical Engineering JournalActa BiomaterialiaACS Applied Materials & Interfaces等国际著名杂志,其中高被引论文1篇,封面论文1篇。Journal of NanobiotechnologyACS Applied Materials & Interfaces等期刊审稿人。协助指导研究生获得国家奖学金、省级/校级优秀毕业生等荣誉。指导本科生荣获“全国大学生药苑论坛”创新成果一等奖和优秀论文奖,立项大学生创新创业课题3项。获优秀学士论文指导教师。

联系方式:luokaipei@cdutcm.edu.cn

二、代表性成果

(一)科研项目

1. 国家自然科学基金青年基金,822046332023.01-2025.1230主持

2. 中国博士后科学基金面上项目,2021M7005502021.12-2024.088主持

3. 四川省自然科学基金面上项目,2022NSFSC06342022.01-2023.1220主持

4. 四川省科教联合基金面上项目,2024NSFSC21122024.11-2026.1020主持

5. 立即博备用网址_立即博赌场-游戏平台“杏林学者”提升计划BSH20210242021.12-2024.0812主持

6. 立即博备用网址_立即博赌场-游戏平台“杏林学者”提升计划QJRC20240212024.12-2026.1118主持

7. 中华中医药学会(2024-2026年度)青年人才托举工程2024-QNRC2-B28主持

(二)学术论文

1. Kaipei Luo*, Lu Yang, Chunmei Yan, Yuxin Zhao, Qiuxia Li, Xing Liu, Long Xie, Qiang Sun, Xiaofang Li*. A dual-targeting liposome enhances triple-negative breast cancer chemoimmunotherapy through inducing immunogenic cell death and inhibiting STAT3 activation. Small, 2023, 19: 2302834.IF: 13.3,中科院一区,封面论文

2. Qiuxia Li, Xing Liu, Chunmei Yan, Bolin Zhao, Yuxin Zhao, Lu Yang, Mingyi Shi, Hua Yu*, Xiaofang Li*, Kaipei Luo*. Polysaccharide-based stimulus-responsive nanomedicines for combination cancer immunotherapy. Small, 2023, 19: 2206211.IF: 13.3,中科院一区)

3. Kaipei Luo, Yunfei Lian, Min Zhang, Hua Yu, Guangji Wang, Juan Li*. Charge convertible biomimetic micellar nanoparticles for enhanced melanoma-targeted therapy through tumor cells and tumor-associated macrophages dual chemotherapy with IDO immunotherapy. Chemical Engineering Journal, 2021, 412: 128659.IF: 16.744,中科院一区)

4. Kaipei Luo, Yi Gao, Shaoping Yin, Yawen Yao, Hua Yu*, Guangji Wang, Juan Li*. Co-delivery of paclitaxel and STAT3 siRNA by multifunctional nanocomplexes for targeted treatment of metastatic breast cancer. Acta Biomaterialia, 2021, 134: 650-664.IF: 10.633中科院一区)

5. Chunmei Yan, Yuxin Zhao, Xiaolian Liu, Yingjie Jiang, Qiuxia Li, Lu Yang*, Xiaofang Li*, Kaipei Luo*. Self-delivery Nano-booster to Enhance Immunogenic Cell Death for Cancer Chemoimmunotherapy. ACS Applied Materials & Interfaces, 2024, 16: 33169-33181.IF: 9.5,中科院二区

6. Chunmei Yan, Qiuxia Li, Qiang Sun, Lu Yang, Xing Liu, Yuxin Zhao, Mingyi Shi, Xiaofang Li*, Kaipei Luo*. Promising nanomedicines of shikonin for cancer therapy. International Journal of Nanomedicine, 2023, 18: 1195-1218.IF: 8.0,中科院二区ESI高被引论文

7. Kaipei Luo, Shaoping Yin, Ruixia Zhang, Hua Yu, Guangji Wang, Juan Li. Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy. International Journal of Pharmaceutics, 2020, 589: 119870.IF: 6.51,中科院二区)

8. Kaipei Luo, Feng Xu, Tianyi Yao, Jianping Zhu, Hua Yu, Guangji Wang, Juan Li*. TPGS and chondroitin sulfate dual-modified lipid-albumin nanosystem enhances the targeted therapy of chemotherapeutic agent against multidrug-resistant cancer. International Journal of Biological Macromolecules, 2021, 183: 1270-1282.IF: 8.025,中科院一区)

9. Yingjie Jiang, Chunmei Yan, Minghao Li, Siying Chen, Zhimin Chen*, Lu Yang*, Kaipei Luo*. Delivery of natural products via polysaccharide-based nanocarriers for cancer therapy: A review on recent advances and future challenges. International Journal of Biological Macromolecules, 2024, 278: 135072.IF: 7.7,中科院一区本科生一作

10. Lu Yang, Xianfeng Liu, Siyin Chen, Jiayi Sun, Yiwen Tao, liyuan Ma, Yong Zeng, Kaipei Luo*, Ruimin Tian*, Xianli Meng*. Scutellarin Ameliorates Mitochondrial Dysfunction and Apoptosis in OGD/R-Insulted HT22 Cells through Mitophagy Induction. Biomedicine & Pharmacotherapy, 2024, 179: 117340.IF: 6.9,中科院二区)

 

 

 


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