立即博备用网址_立即博赌场-游戏平台

图片

图片

官方QQ
官方微信
手机版
您的位置:首页 >师资队伍>本科师资>详细内容

本科师资

谢 欣

来源: 发布时间:2021-07-09 15:01:57 浏览次数: 【字体:

f9e74ccd07dd4eb0845213ce6b6410c4.jpg

    谢欣,医学博士/博士后,高级实验师,医学技术学院教职工第一党支部书记。主要研究方向为中药药效物质的分子作用机制和多维构效关系阐明、中药活性成分的结构修饰及中药新药发现。曾获立即博备用网址_立即博赌场-游戏平台四川省科技进步一等奖(第七完成人)。

    先后主持国家博士后课题2项(面上项目1项及特别资助项目1项)、四川省科技厅项目1项、立即博备用网址_立即博赌场-游戏平台“杏林学者”课题3项;参与国家自然基金5项。相关成果发表在Chemical Communications; Advanced Synthesis & Catalysis; Synletter;The Chemical Record 等知名期刊,共计SCI收录15篇,其中以第一作者或通讯发表SCI论文10篇、其中IF大于5论文8篇,学科领域JCR一区论文3篇、ESI高被引论文1篇。获得国家授权发明专利5项;参编专著5部。


    ※ 近年来主要代表性论文

[1] Xie, X.;   Xiong, S.-S.;  Li, X.;  Huang, H.;   Wu, F.-B.; Shen, P.-F.; Cheng Peng, He, G.*; Han, B.* Design and organocatalytic synthesis of spirooxindole–cyclopentene–isoxazole hybrids as novel MDM2–p53 inhibitors. Organic Chemistry Frontiers 2021,8, 1836-1843. IF 5.155

[2]Xie, X.; Xiang, L.; Peng, C.*; Han, B*. Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry. Chemical Record 2019, 19(11), 2209.  IF: 6.163

[3]Xie, X.; Huang, W.; Peng, C.*; Han, B.* Organocatalytic Asymmetric Synthesis of Six-Membered Carbocycle-Based Spiro Compounds. Advanced Synthesis & Catalysis 2018, 360, 194-228. IF 5.646

[4] Xie, X.; Peng, C.*; He, G.; Leng, H.-J.; Wang, B.; Huang, W.*; Han, B.* Asymmetric synthesis of a structurally and stereochemically complex spirooxindole pyran scaffold through an organocatalytic multicomponent cascade reaction. Chemical Communications 2012, 48(85): 10487.  IF: 5.996

[5]Xie, X.; Peng C. *; Leng H. J.; Wang B.; Tang Z. W.; Huang W*. Asymmetric synthesis of oxa-spirocyclic indanones with structural complexity via an organocatalytic Michael–Henry–Acetalization cascade. Synlett 2014, 25, 143-147. IF 2.419

[6]Mu, J.?; Xie, X.?; Xiong, S.-S.; Zhang, Y.-H.; Wang, Y.-T.; Zhao, Q.; Zhu H.-P.; Huang, W.*; He, G.* Discovery of spirooxindole–ferrocene hybrids as novel MDM2 inhibitors. Chinese Chemical Letters 2021, 32, 1897-1901.  IF 4.632

[7]Han, B.?; Xie, X.?; Huang, W.; Li, X.; Yang, L.; Peng, C.* Organocatalytic Morita-Baylis-Hillman/Michael/Acetalization Cascade: Procedure-Controlled Diastereodivergence in the Asymmetric Synthesis of Fully Substituted Tetrahydropyrans. Advanced Synthesis & Catalysis 2014, 356(17), 3676.   IF: 5.851

[8]Tang, Z. W.?; Xie, X.?; Huang, W.; Leng, H. J.; Wang, B.; Han, B.*; Peng, C.* Exploring the Antibacterial Target of the Main Constituent of Pogostemon cablin by using Molecular Docking and Network Analysis. Latin American Journal of Pharmacy 2016, 35, 502-509. IF 0.298


    ※ 近年来主出版专著

(1)中国临床药物大词典. 中药饮片卷. 中国医药科技出版社. 常务编委. 2018

(2)中国临床药物大词典. 成方制剂卷. 中国医药科技出版社. 常务编委. 2018

(3)有毒中药附子、川乌、草乌的安全性评价与应用. 四川科学技术出版社. 编委. 2014

(4)中华道地药材. 中国中医药出版社. 编委. 2013


终审:医技办公室管理员