个人简介
潘校琦,浙江淳安人,教授,硕士生导师,华中科技大学劳动卫生与环境卫生学博士,中药学博士后,预防医学教研室主任,英国牛津大学访问学者,劳动卫生与环境卫生学学科负责人,四川省中医药管理局学术和技术带头人后备人选。
学会任职
世界中医药学会联合会道地药材多维评价专委会理事,中国毒理学会毒理学教育专委会青年委员,四川省疫情防控与公共卫生研究智库专家,四川省预防医学会环境卫生分会常务委员,四川省环境诱变剂学会副秘书长,四川省预防医学会老年疾病预防与控制分会委员。
研究方向
(1)环境毒理与中医药解毒机制研究
(2)大气颗粒物及其组分与疾病分布的关联性研究
(3)中医药大健康相关产品研发
科研项目
(1)国家自然科学基金委员会,青年科学基金项目,82004056,多巴胺神经递质-受体系统介导的cAMP/PKA-Ca2+信号轴在附子神经毒性中的作用及机制研究,2021-01至2023-12,24万元,主持
(2)国家自然科学基金委员会,重大项目,81891012,中药道地性“性-效”关系研究,2019-01至2023-12,395万元,参与
(3)国家自然科学基金委员会,区域创新发展联合基金,川产道地药材附子“去性存用”配伍治疗RA和BPH的增效解毒机制研究,2025-01至2028-12,260万元,参与
(4)四川省科技厅,自然科学基金,2023NSFSC1774,基于分子对接与钙成像动力学技术高通量筛选靶向溶酶体TPC2中药活性化合物,2023-01至2024-12,10万元,主持
(5)中国博士后科学基金会,面上资助,2018M631070,基于AMPK调控线粒体能量代谢研究附子神经毒性分子机制,2018-02至2020-09,8万元,主持
(6)成都市委校联合基金,联合创新专项,WXLH202402030,基于多组学与高通量筛选研究英夫利西单抗与中药协同治疗难治型溃疡性结肠炎的作用及机制,2024-12至2026-12,20万元,主持
发表论文(第一作者或通讯作者)
[1] Li Yuanyuan, Zhang Tingting, Mou Qiaoxing, Liu Sirui, Wu Wanxing, Wang Simei, Yan Xiaoyu, Liang Jie, Yan Mengfan, Liu Weiying#, Pan Xiaoqi#. Overexpression of Methionine Sulfoxide Reductase A Alleviates Acrylamide-Induced Neurotoxicity by Mitigating Lipid Peroxidation and Mitochondria-Dependent Apoptosis In Vivo and In Vitro. Food and Chemical Toxicology. 2025, 20:115339.
[2] Pan Xiaoqi#, Liang Tianyu, Feng Han, Liu Weiying, Mou Qiaoxin, Yan Xiaoyu#. Toxicological landscape of Fuzi: a comprehensive study on the spatial distribution of toxicants and regional neurotoxicity variability in zebrafish. Frontiers in Pharmacology. 2025, 15:1500527.
[3] Yan Xiaoyu, Li Qiuju, Wu Shuangyue, Liang Jie, Li Yuanyuan, Zhang Tignting, Chen Dayi#, Pan Xiaoqi#. Acrylamide induces the activation of BV2 microglial cells through TLR2/4-mediated LRRK2-NFATc2 signaling cascade. Food and Chemical Toxicology. 2023, 176:113775.
[4] Li Qiuju, Peng Fu, Yan Xiaoyu, Chen Yan, Zhou Jie, Wu Shuangyue, Jiang Wanyanhan, Jin Xuhui, Liang Jie, Peng Cheng#, Pan Xiaoqi#. Inhibition of SLC7A11-GPX4 signal pathway is involved in aconitine-induced ferroptosis in vivo and in vitro. Journal of Ethnopharmacology, 2023, 303:116029.
[5] Zhou Jie, Peng Cheng, Li Qiuju, Yan Xiaoyu, Yang Liang, Li Mengting, Cao Xiaoyu, Xie Xiaofang, Chen Dayi, Rao Chaolong, Huang Sizhou, Peng Fu#, Pan Xiaoqi#. Dopamine homeostasis imbalance and dopamine receptors-mediated AC/cAMP/PKA pathway activation are involved in aconitine-induced neurological impairment in zebrafish and SH-SY5Y cells. Frontiers in Pharmacology. 2022, 13: 837810.
[6] Li Qiuju, Yan Xiaoyu, Zhang Ying, Zhou Jie, Yang Liang, Wu Shuangyue, Peng Cheng#, Pan Xiaoqi#. Risk compounds, potential mechanisms and biomarkers of traditional Chinese medicine-induced reproductive toxicity. Journal of Applied Toxicology. 2022, 1-23.
[7] Wang Wenlin, Jiang Jialuo, Huang Yan, Peng Fu, Hu Tingting, Wu Jiayang, Pan Xiaoqi#, Rao Chaolong#. Aconitine induces autophagy via activating oxidative DNA damage-mediated AMPK/ULK1 signaling pathway in H9c2 cells. Journal of Ethnopharmacology. 2022, 282: 114631.
[8] Yang Liang, Chen Yan, Zhou Jie, Sun Jiayi, Jiang Wanyanhan, Liu Tianyu, Rao Chaolong#, Pan Xiaoqi#. Aconitine induces mitochondrial energy metabolism dysfunction through inhibition of AMPK signaling and interference with mitochondrial dynamics in SH-SY5Y cells. Toxicology Letters. 2021, 347: 36-44.
[9] Zhou Jie, Peng Fu, Cao Xiaoyu, Xie Xiaofang, Chen Dayi, Yang Liang, Rao Chaolong, Peng Cheng#, Pan Xiaoqi#. Risk compounds, preclinical toxicity evaluation, and potential mechanisms of Chinese mteria medica-induced cardiotoxicity. Frontiers in Pharmacology. 2021, 12: 578796.
[10] Peng Fu, Fan Huali, Li Sui, Peng Cheng#, Pan Xiaoqi#. MicroRNAs in Epithelial-Mesenchymal Transition Process of Cancer: Potential Targets for Chemotherapy. International Journal of Molecular Sciences. 2021, 22(14):7526.
[11] Pan Xiaoqi, Zhou Jie, Chen Yan, Xie Xiaofang, Rao Chaolong, Liang Jie, Zhang Ying, Peng Cheng#. Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury. Toxicology Letters. 2020, 323: 48-56.
通讯方式
立即博备用网址_立即博赌场-游戏平台公共卫生学院
四川省成都市温江区柳台大道1166号,611137
E-mail:panxiaoqi1104@cdutcm.edu.cn