陈伟
个人简介
陈伟，生物信息学与计算生物学课题组组长，教授，博士/硕士研究生导师。中国计算机学会生物信息学专委会委员、中国人工智能学会生物信息学专委会委员、中国生物工程学会生物信息学专委会委员、中国生物信息学会(筹)理事，Molecular Therapy-Nucleic Acids期刊副主编。发表了原创性SCI论文160余篇，累积引用17000余次，入选Elsevier中国高被引学者和“终身科学影响力排行榜”榜单。
研究方向：
生物信息学和系统生物学。基于人工智能方法开展多组学数据分析算法开发、中医药大数据挖掘、药物发现与设计等方面的研究。
代表性成果：
1. Wei Chen*, Chi Song, Liang Leng, Sanyin Zhang, Shilin Chen*. The Application of Artificial Intelligence Accelerates G Protein-Coupled Receptor Ligand Discovery. Engineering, 2023, 10.1016/j.eng.2023.09.011.
2. Fanbo Meng, Tianzhe Chu, Pengmian Feng, Nan Li, Chi Song, Chunjin Li, Liang Leng*, Xiaoming Song*, Wei Chen*. Genome assembly of Polygala tenuifolia provides insights into its karyotype evolution and triterpenoid saponin biosynthesis. Horticulture Research, 2023, 10: uhad139.
3. Wei Chen, Xuesong Liu, Sanyin Zhang, Shilin Chen*. Artificial Intelligence for Drug Discovery: Resources, Methods, and Applications. Molecular Therapy-Nucleic Acids, 2023, 31: 691-702.
4. Fanbo Meng, Qiang Tang, Tianzhe Chu, Xianhai Li, Yue Lin, Xiaoming Song*, Wei Chen*. TCMPG: an integrative database for traditional Chinese medicine plant genomes. Horticulture Research, 2022, 9: uhac060
5. Qiang Tang, Fulei Nie, Qi Zhao*, Wei Chen*. A merged molecular representation deep learning method for blood-brain barrier permeability prediction. Briefings in Bioinformatics, 2022, 23(5):1-10.
6. Xianhai Li, Qiang Tang, Fanbo Meng, Pufeng Du*, Wei Chen*. INPUT: An intelligent network pharmacology platform unique for traditional Chinese medicine. Computational and Structural Biotechnology Journal, 2022, 20: 1345-1351.
7. Qiang Tang, Fulei Nie, Juanjuan Kang, Wei Chen*. mRNALocater: Enhance the prediction accuracy of eukaryotic mRNA subcellular localization by using model fusion strategy. Molecular Therapy, 2021, 29(8):2617-2623
8. Fanbo Meng, Tianzhe Chu, Qiang Tang, Wei Chen*. A tetraploidization event shaped the Aquilaria sinensis genome and contributed to the ability of sesquiterpenes synthesis. BMC Genomics, 2021, 22(1):647.
9. Liangsheng Zhang*, Fei Chen, Xingtan Zhang, Zhen Li, Yiyong Zhao, …, Jihua Wang, Wei Chen, …, Guanhua Liu, Jianyu Fu, Feng Chen, Hong Ma, Yves Van de Peer, Haibao Tang. The water lily genome and the early evolution of flowering plants. Nature, 2020, 577:79-84.
10. Andrew H. Paterson*, Jonathan F. Wendel, Heidrun Gundlach, Hui Guo, Jerry Jenkins, Dianchuan Jin, Danny Llewellyn, Kurtis C. Showmaker, Shengqiang Shu, Joshua Udall, Mi-jeong Yoo, Robert Byers, Wei Chen, Adi Doron-Faigenboim, …, Jeremy Schmutz*. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fiber. Nature, 2012(492):423-427.